Ebola Spread Has Slowed in Liberia, C.D.C. Says

The international response to West Africa’s Ebola epidemic, coupled with more effective action by local communities, has stopped the exponential spread of the disease in one of the hardest-hit countries, Liberia, the director of theCenters for Disease Control and Preventionsaid on Thursday.

In confirming what health officials and news organizations had reported for weeks, Dr. Thomas R. Frieden, the C.D.C. director, said that a previous worse-case projection by the agency that the Ebola epidemic could lead to 1.4 million cases by late January unless effective measures were taken to contain it was no longer applicable, crediting what he called “good progress” in Liberia.

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Treating Ebola: The Hunt for a Drug

Although there are currently no drugs or vaccines approved in the United States to treat or prevent Ebola, health officials have used several experimental drugs in the recent epidemic.

The Ebola Drug Pipeline

The World Health Organization has said that it is ethical to use unproven drugs in the current epidemic. In the United States, the Food and Drug Administration has granted expanded access to several experimental drugs for use on Ebola patients. The drugs prevent replication of Ebola virus and the vaccines work by triggering an immune response. The drugs and vaccines listed here are in clinical trials and have received support for further development, according to the Centers for Disease Control and Prevention.

Animals

Trials

Healthy

volunteers

Small group

of patients

Large group

of patients

Approved

for use

ZMapp

Brincidofovir

Drugs

TKM-Ebola

Favipiravir

AVI-7537

BCX4430

ChAd3

Vaccines

VSV-EBOV

What Patients Have Been Given Outside West Africa

A dozen patients outside West Africa have been treated with experimental drugs. Because the sample size is small and many patients have received multiple treatments, it is difficult to determine whether a particular drug has been effective.

Oslo

London

Frankfurt

Paris

Omaha

Nebraska Medical Center

Madrid

Bethesda, Md.

N.I.H. Clinical Center

Dallas

Atlanta

Emory University Hospital

Countries with Ebola outbreaks

 ZMapp 

 Brincidofovir 

 TKM-Ebola 

 Favipiravir 

 Blood transfusion 

 Not disclosed

U.S.	Aid worker		Recovered
	Missionary		Recovered
	Doctor		Recovered
	Visitor		Died
	NBC Cameraman		Recovered
	Nurse		Recovered

Spain	Priest		Died
	Nurse		Recovered

France	Nurse		Recovered

Britain	Nurse		Recovered

Germany	Physician		In treatment

Norway	Aid worker		Recovered

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