Wednesday, November 26, 2014

Why Americans Call Turkey 'Turkey' *

ZACH GOLDHAMMER



Flickr/The Atlantic
Within the turkey lies the tangled history of the world.
OK, not quite. But not far off, either.
"Turkey" the bird is native to North America. But "turkey" the word is a geographic mess—a tribute to the vagaries of colonial trade and conquest. As you might have suspected, the English term for the avian creature likely comes from Turkey the country. Or, more precisely, from Turkish merchants in the 15th and 16th centuries.
How exactly the word "turkey" made its way into the English language is in dispute. The linguist Mario Pei theorized that more than five centuries ago, Turks from the commercial hub of Constantinople (which the Ottomans conquered in the mid-15th century) sold wild fowl from Guinea in West Africa to European markets, leading the English to refer to the bird as “turkey cock” or “turkey coq” (coq being French for “rooster”), and eventually “turkey” for short. When British settlers arrived in Massachusetts, they applied the same terms to the wild fowl they spotted in the New World, even though the birds were a different species than their African counterparts. The etymology expert Mark Forsyth, meanwhile, claims that Turkish traders brought guinea fowl to England from Madagascar, off the coast of southeast Africa, and that Spanish conquistadors then introduced American fowl to Europe, where they were conflated with the “turkeys” from Madagascar. Dan Jurafsky, another linguist, argues that Europeans imported guinea fowl from Ethiopia (which was sometimes mixed up with India) via the Mamluk Turks, and then confused the birds with North American fowl shipped across the Atlantic by the Portuguese.
The guinea fowl (left) vs.
the North American turkey (Wikipedia)
Here’s where things get even more bewildering. Turkey, which has no native turkeys, does not call turkey "turkey." The Turks “knew the bird wasn’t theirs,” Forsyth explains, so they “made a completely different mistake and called it a hindi, because they thought the bird was probably Indian.” They weren't alone. The French originally called the American bird poulet d’Inde (literally “chicken from India”), which has since been abbreviated to dinde, and similar terms exist in languages ranging from Polish to Hebrew to Catalan. Then there’s the oddly specific Dutch word kalkoen, which, as a contraction of Calicut-hoenliterally means “hen from Calicut,” a major Indian commercial center at the time. These names may have arisen from the mistaken belief at the time that the New World was the Indies, or the sense that the turkey trade passed through India.
So what is the bird called in India? It may be hindi in Turkey, but in Hindi it’s ṭarki. Some Indian dialects, however, use the word piru or peru, the latter being how the Portuguese refer to the American fowl, which is not native to Peru but may have become popular in Portugal as Spanish and Portuguese explorers conquered the New World. The expansion of Western colonialism only complicated matters: Malaysians call turkey ayam blander (“Dutch chicken”), while Cambodians opt for moan barang (“French chicken”).
Then there are the turkey truthers and linguistic revisionists. In the early 1990s, for instance, a debate broke out in the “letter to the editor” section of The New York Times over the possible Hebrew origins of the word "turkey." On December 13, 1992, Rabbi Harold M. Kamsler suggested (as a follow-up to a Thanksgiving-themed piece titled “One Strange Bird”) that the New World fowl received its English name from Christopher Columbus’s interpreter, Luis de Torres, a Jewish convert to Catholicism. In an October 12, 1492 letter to a friend in Spain, de Torres had referred to the American bird he encountered as a tuki, the word for “peacock” in ancient Hebrew and “parrot” in modern Hebrew (a more dubious version of this story claims that Columbus himself was a Jew who hid his identity in the aftermath of the Spanish Inquisition but drew on his lineage to christen the fowl).
Kamsler’s letter, however, was met with a firm rebuttal from the president of the Association for the Study of Jewish Languages, David L Gold. “Rabbi Kamsler's explanation, not original with him, is an old yarn spun in uninformed Jewish circles,” Gold wrote. “Along with countless other pseudoscientific claims about supposed Hebrew influence on English and other languages, the myth of the Hebrew origin of ‘turkey’ was quietly exploded in volume 2 of Jewish Linguistic Studies (1990).”
The turkey’s scientific name doesn't make much more sense than its vernacular one. Its binomial nomenclature, Meleagris gallopavo, is a hodgepodge. The first name comes from a Greek myth in which the goddess Artemis turned the grieving sisters of the slain Meleager into guinea fowls. The second name is a portmanteau: Gallo is derived from the Latin word for rooster, gallus, while pavo is the Latin word for peacock. So, effectively, the official name for a turkey is guinea-fowl-rooster-peacock.
Reflecting on his interview with Mario Pei, NPR’s Robert Krulwich noted that “for 500 years now, this altogether American, very gallant if not particularly intelligent animal has never once been given an American name.” But the turkey does have many authentically American names—Americans just choose not to use them. After all, pre-Aztec and Aztec peoples domesticated the turkey more than a millennium before Columbus reached the New World (the Aztecs called the bird huehxolotl). There are numerous Native American words for the bird, including the Blackfoot termomahksipi’kssii, which literally means “big bird.” It’s a bit vague, sure, but it certainly beats guinea-fowl-rooster-peacock.

http://m.theatlantic.com/international/archive/2014/11/why-americans-call-turkey-turkey/383225/

*I know this article is quiet unrelated to what we are supposed to share, but it is at least Thanksgiving themed. 

Tuesday, November 25, 2014

Gut–brain link grabs neuroscientists

NATURE | NEWS
Idea that intestinal bacteria affect mental health gains ground.

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Lester V. Bergman/Corbis
Feeding mice the bacterium Bacteroides fragilis can reverse autism-like symptoms.
Companies selling ‘probiotic’ foods have long claimed that cultivating the right gut bacteria can benefit mental well-being, but neuroscientists have generally been sceptical. Now there is hard evidence linking conditions such as autism and depression to the gut’s microbial residents, known as the microbiome. And neuroscientists are taking notice — not just of the clinical implications but also of what the link could mean for experimental design.
“The field is going to another level of sophistication,” says Sarkis Mazmanian, a microbiologist at the California Institute of Technology in Pasadena. “Hopefully this will shift this image that there’s too much commercial interest and data from too few labs.”
This year, the US National Institute of Mental Health spent more than US$1 million on a new research programme aimed at the microbiome–brain connection. And on 19 November, neuroscientists will present evidence for the link in a symposium at the annual Society for Neuroscience meeting in Washington DC called ‘Gut Microbes and the Brain: Paradigm Shift in Neuroscience’.
Although correlations have been noted between the composition of the gut microbiome and behavioural conditions, especially autism1, neuroscientists are only now starting to understand how gut bacteria may influence the brain. The immune system almost certainly plays a part, Mazmanian says, as does the vagus nerve, which connects the brain to the digestive tract. Bacterial waste products can also influence the brain — for example, at least two types of intestinal bacterium produce the neurotransmitter γ-aminobutyric acid (GABA)2.
The microbiome is likely to have its greatest impact on the brain early in life, says pharmacologist John Cryan at University College Cork in Ireland. In a study to be presented at the neuroscience meeting, his group found that mice born by caesarean section, which hosted different microbes from mice born vaginally, were significantly more anxious and had symptoms of depression. The animals’ inability to pick up their mothers’ vaginal microbes during birth — the first bacteria that they would normally encounter — may cause lifelong changes in mental health, he says.
Similarly, a 2013 study from Mazmanian’s lab found that a mouse model with some features of autism had much lower levels of a common gut bacterium called Bacteroides fragilis than did normal mice3. The animals were also stressed, antisocial and had gastrointestinal symptoms often seen in autism. Feeding B. fragilis to the mice reversed the symptoms. The group also found that the mice with these symptoms had higher levels of a bacterial metabolite called 4-ethylphenylsulphate (4EPS) in their blood, and that injecting that chemical into normal mice caused the same behavioural problems.
The mechanism for these effects is still unclear. At the meeting, Mazmanian will present data showing that feeding 4EPS to mice causes behavioural problems only if the gut is leaky, presumably because that allows the chemical to seep into the body through the intestinal wall. That observation raises the possibility that some people with autism could be supported with therapies, such as probiotics, that target the gut instead of the brain, which is a much more complex and inaccessible organ.
Yet even those at the forefront of the research remain sceptical that the findings will translate into treatments for humans. The evidence that probiotics affect human behaviour “is minimal to say the least”, Mazmanian acknowledges. Still, he says, a growing number of researchers are starting to look at some mental illnesses through a microbial lens.
There are implications for basic research too. In another study to be presented at the meeting, veterinarian Catherine Hagan at the University of Missouri in Columbia compared the gut bacteria in laboratory mice of the same genetic strain that had been bought from different vendors. Their commensals differed widely, she found: mice from the Jackson Laboratory in Bar Harbor, Maine, for instance, had fewer bacterial types in their guts than did mice from Harlan Laboratories, which is headquartered in Indianapolis, Indiana.
Such differences could present a major complication for researchers seeking to reproduce another lab’s behavioural experiments, Hagan says. When her team transplanted bacteria from female Harlan mice into female Jackson mice, the animals became less anxious and had lower levels of stress-related chemicals in their blood. Hagan notes that when a lab makes a mouse by in vitrofertilization, the animal will pick up microbes from its surrogate mother, which might differ greatly from those of its genetic mother. “If we’re going to kill animals for research, we want to make sure they’re modelling what we think they’re modelling,” she says.

Monday, November 24, 2014

Turtles and dinosaurs: Scientists solve reptile mysteries with landmark study on the evolution of turtles



Date:
November 24, 2014
Source:
California Academy of Sciences
Summary:
A team of scientists has reconstructed a detailed 'tree of life' for turtles. Next generation sequencing technologies have generated unprecedented amounts of genetic information for a thrilling new look at turtles' evolutionary history. Scientists place turtles in the newly named group 'Archelosauria' with their closest relatives: birds, crocodiles, and dinosaurs.

Turtles -- like this alligator snapping turtle Macrochelys temminckii -- are a diverse group of animals with a hotly contested evolutionary history. Researchers from the California Academy of Sciences used a next-generation genetic sequencing technique to reconstruct a robust turtle 'tree of life' and fill-in existing knowledge gaps.
Credit: The California Academy of Sciences

Read more: http://www.sciencedaily.com/releases/2014/11/141124103225.htm

Friday, November 21, 2014

F.D.A. Approves Hysingla, a Powerful Painkiller


The Food and Drug Administration on Thursday approved a long-acting opioid painkiller that contains pure hydrocodone, which some addiction experts fear will be abused.
The new drug, Hysingla, and another drug approved earlier this year, Zohydro, contain pure hydrocodone, a narcotic, without the acetaminophen used in other opioids. But Hysingla is to be made available as an “abuse-deterrent” tablet that cannot easily be broken or crushed by addicts looking to snort or inject it.
Nearly half of the nation’s overdose deaths involved painkillers like hydrocodone and oxycodone, according to a 2010 study by the Centers for Disease Control and Prevention. More than 12 million people used prescription painkillers for nonmedical reasons that year, according to the study.
Prescription opioid abuse kills more adults annually than heroin and cocaine combined, and sends 420,000 Americans to emergency rooms every year, according to the C.D.C.
Hysingla, however, will not be not abuse-proof, said officials at the F.D.A. and the drug’s manufacturer, Purdue Pharma. Its extended-release formulation, a pill to be taken once every 24 hours by patients requiring round-the-clock pain relief, will contain as much as 120 milligrams of hydrocodone.
The F.D.A. warned that doses of 80 milligrams or more “should not be prescribed to people who have not previously taken an opioid medication,” but officials described the abuse-deterrent formulation as a step forward.
“For patients who benefit from hydrocodone alone for the treatment of pain severe enough to need an opioid, this offers the advantage of once-a-day dosing in a formulation that we expect will reduce abuse and misuse,” said Dr. Douglas Throckmorton, deputy center director for regulatory programs at the F.D.A.
An official with Purdue Pharma said concerns about prescription-painkiller deaths were what motivated the company to develop abuse-deterrent products.
The tablets are hard and difficult to crush, and when mixed with water or other fluids, they become a “gelatinous, gooey mass that doesn’t pull into a syringe easily,” said Dr. David Haddox, the company’s chief of health policy.
“This is coming on to a market that is currently flooded with products that do not have abuse-deterrent options,” added Raul Damas, the company’s spokesman.
Dr. Andrew Kolodny, the chief medical officer at Phoenix House, a group of nonprofit addiction-treatment centers, said he was disturbed by the drug’s approval and disappointed that the F.D.A. did not seek input from an advisory committee of experts.
Dr. Kolodny said that addicts knew how to break down abuse-deterrent products for oral use, and that the 120-milligram tablets were particularly dangerous because they “pack an enormous amount of hydrocodone.”
The F.D.A. approved Zohydro last year despite the recommendation of its own expert advisory committee, which had voted against approval.

Ebola Spread Has Slowed in Liberia, C.D.C. Says

The international response to West Africa’s Ebola epidemic, coupled with more effective action by local communities, has stopped the exponential spread of the disease in one of the hardest-hit countries, Liberia, the director of theCenters for Disease Control and Preventionsaid on Thursday.
In confirming what health officials and news organizations had reported for weeks, Dr. Thomas R. Frieden, the C.D.C. director, said that a previous worse-case projection by the agency that the Ebola epidemic could lead to 1.4 million cases by late January unless effective measures were taken to contain it was no longer applicable, crediting what he called “good progress” in Liberia.
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Treating Ebola: The Hunt for a Drug



The Ebola Drug Pipeline

The World Health Organization has said that it is ethical to use unproven drugs in the current epidemic. In the United States, the Food and Drug Administration has granted expanded access to several experimental drugs for use on Ebola patients. The drugs prevent replication of Ebola virus and the vaccines work by triggering an immune response. The drugs and vaccines listed here are in clinical trials and have received support for further development, according to the Centers for Disease Control and Prevention.
Animals
Trials
Healthy
volunteers
Small group
of patients
Large group
of patients
Approved
for use
ZMapp
Brincidofovir
Drugs
TKM-Ebola
Favipiravir
AVI-7537
BCX4430
ChAd3
Vaccines
VSV-EBOV

What Patients Have Been Given Outside West Africa

A dozen patients outside West Africa have been treated with experimental drugs. Because the sample size is small and many patients have received multiple treatments, it is difficult to determine whether a particular drug has been effective.
Oslo
London
Frankfurt
Paris
Omaha
Nebraska Medical Center
Madrid
Bethesda, Md.
N.I.H. Clinical Center
Dallas
Atlanta
Emory University Hospital
Countries with Ebola outbreaks
 ZMapp 
 Brincidofovir 
 TKM-Ebola 
 Favipiravir 
 Blood transfusion 
 Not disclosed
U.S.Aid workerRecovered
MissionaryRecovered
DoctorRecovered
VisitorDied
NBC CameramanRecovered
NurseRecovered
SpainPriestDied
NurseRecovered
FranceNurseRecovered
BritainNurseRecovered
GermanyPhysicianIn treatment
NorwayAid workerRecovered

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Hos

Tuesday, November 18, 2014

Philae’s 64 hours of comet science yield rich data

NATURE | NEWS


Comet lander is now hibernating, but has already altered our understanding of these objects.

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ESA/Rosetta/Philae/CIVA
The European Space Agency’s Philae probe successfully landed on 67P/Churyumov–Gerasimenko, sending back the first ever image from a comet’s surface.
“I get goose bumps talking about this image,” says Holger Sierks. The photo is of a metallic, robotic leg against the rugged surface of comet 67P/Churyumov–Gerasimenko. For Sierks, principal investigator of the OSIRIS camera on the Rosetta spacecraft, which put the robotic lander on the comet, it is the “image of my life”.
But that was not before Philae gave each of its ten instruments a chance to gather and transmit data. Although the plan was for Philae to still be collecting data now, powered by its solar panels, findings from just 64 hours of scientific activity are already changing the way that scientists view comets.The European Space Agency (ESA) mission made history on 12 November when the three-legged Philae probe landed on Churyumov–Gerasimenko, which is 4 kilometres in diameter, travels at more than 60,000 kilometres per hour and is currently 514 million kilometres from Earth. After a nail-biting three days in which the elation of Philae’s touchdown gave way to fears about its power levels after it ended up at a site almost devoid of sunlight, the lander went into a potentially terminal standby on 15 November, its batteries drained.
Twice a day, Philae had a contact window of 3–4 hours in which to communicate with mission control through the Rosetta orbiter. That was enough to achieve 90% of what scientists had hoped for, says Monica Grady, a co-investigator on Philae’s chemical analyser, Ptolemy. And for some instruments, the lander’s unplanned bounces across the comet surface — which saw it end up in a shady spot — might actually have spawned data that are more interesting than anticipated.
J. Mai/ESA
Mission scientists celebrated Philae’s separation.
Philae’s dramas began the night before the scheduled landing, with computing problems. A reboot fixed those, and the team decided to go ahead despite a second issue with the lander’s thrusters, which were intended to press Philae into the comet’s surface until it secured itself. But then another mechanism, the harpoons that were intended to securely attach the lander, also failed to fire on touchdown. Even as champagne corks popped at the European Space Operations Centre in Darmstadt, Germany, ESA scientists were unaware that Philae was already rebounding. It bounced twice — once rising as high as 1 kilometre above the comet’s rotating surface — before the weak gravity, under which a craft weighing 100 kilograms on Earth would weigh just 1 gram, eventually brought the lander to rest.
Philae originally hit the flat, sunny region that had been carefully selected as its landing spot, but after the acrobatics, it ended up 1 kilo­metre away on its side, with one leg raised off the surface, in the shadow of a rocky-looking cliff face. From this inelegant position, where it received just 1.5 hours of sunlight in every 12.4-hour comet rotation, it did not have enough power to charge its secondary batteries.

Comet relief

Despite the bumpy landing, Philae’s 64 hours of activity pulled in a haul of good data, which are still being processed. The first panoramic pictures from its CIVA (Comet Nucleus Infrared and Visible Analyser) camera show a surface covered in dust and debris, with rock-like materials in a range of sizes. “It’s certainly rougher than what we thought,” says Stephan Ulamec, Philae project manager at the German Aerospace Center (DLR) near Cologne.
Data from another instrument, MUPUS (Multi-purpose Sensors for Surface and Sub-Surface Science), which includes a Coke-can-sized hammer mechanism atop a 40-centimetre-long rod to probe the comet’s surface, revealed a surprise: the comet seems to have hard ice underneath a 10–20-centimetre layer of dust, into which the hammer could not probe. “We were expecting a softer layer, with a consistency like compact snow, or maybe chalk,” says the DLR’s Tilman Spohn, principal investigator for MUPUS.

Asteroids on the agenda

As their European colleagues put a lander on a comet, US space scientists were thrilled — and a little envious. “It was not perfect, but it was amazing,” says Jessica Sunshine, who studies comets at the University of Maryland in College Park. 
Sunshine’s team designed a ‘comet hopper’ that would have used nuclear batteries to jump slowly across a comet’s surface, but NASA declined to fund it in 2012. Now the team is working on an alternative proposal to build on the questions that Philae is starting to raise.
But first, the focus is shifting to asteroids. On 30 November, the Japan Aerospace and Exploration Agency plans to launch its Hayabusa-2 mission to the asteroid 1999 JU3, which will carry, among other things, a Philae-like lander. In September 2016, NASA aims to launch the OSIRIS-REx probe, which will use a robotic arm to vacuum up samples from the asteroid Bennu, for return to Earth.
Rosetta scientists spent several months studying their comet before deciding where they would touch down; the OSIRIS-REx team plans to do the same. “One of the hard things about going to these bodies is that we don’t know what they look like,” says principal investigator Dante Lauretta, of the University of Arizona in Tucson.
Congressman Lamar Smith (Republican, Texas), who heads the House of Representatives committee that oversees science and space issues, notes that Rosetta launched more than a decade ago. “We must make long-term commitments today,” he says, “if we want to ensure successes in space in the future.”
The hardness of this sub-surface will, along with temperature measurements, help scientists to piece together how the comet’s coma of gas and dust forms. But it will have to be reconciled with the low density of the comet, Spohn says. It could be that the ice is porous, or that the hardness is specific to the cold, dark region where Philae came to rest.
Another instrument on the lander, ROMAP (Rosetta Magnetometer and Plasma Monitor), probably benefited from Philae’s two bounces. ROMAP will help to answer whether the comet has its own magnetic field — which could have ramifications for models of planet formation — and how the ionized gas that envelops the comet changes near its surface; the bounces mean extra data points. “If someone designed a mission for magnetometers, and he was a very creative person, he would have done it exactly like that,” says Uli Auster, ROMAP’s co-principal investigator.
Shortly after touchdown, organic molecules were detected in samples of the comet’s surface, courtesy of COSAC, the Cometary Sampling and Composition experiment. It is designed to probe for such molecules and test whether their handedness, or chirality, matches with chemical signatures on Earth. But COSAC had to wait until the final hours of Philae’s battery life before attempting to probe the sub-surface because of fears that the drill action would cause the unanchored lander to tip over. 
More data could yet arrive. Before Philae shut down, the team instructed it to turn about 35 degrees and lift its body by 4 centimetres to bring the craft’s largest solar panel into the light. It could wake up if warming conditions allow it to generate enough power to restart as the comet gets closer to the Sun.
In August, the comet reaches perihelion, its closest point to the Sun, and it will become “active like hell”, says Sierks. The shade that shut down the lander in its first days may become its welcome parasol, says Meierhenrich. “Now it may survive much longer than March. Maybe in April, May or June we might regain contact.”

Coal Rush in India Could Tip Balance on Climate Change




Photo

A mine in Jharkhand State. India’s coal rush could push the world past the brink of irreversible climate change, scientists say. CreditKuni Takahashi for The New York Times

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DHANBAD, India — Decades of strip mining have left this town in the heart of India’s coal fields a fiery moonscape, with mountains of black slag, sulfurous air and sickened residents.
But rather than reclaim these hills or rethink their exploitation, the government is digging deeper in a coal rush that could push the world into irreversible climate change and make India’s cities, already among the world’s most polluted, even more unlivable, scientists say.
“If India goes deeper and deeper into coal, we’re all doomed,” said Veerabhadran Ramanathan, director of the Center for Atmospheric Sciences at the Scripps Institution of Oceanography and one of the world’s top climate scientists. “And no place will suffer more than India.”


India’s coal mining plans may represent the biggest obstacle to a global climate pact to be negotiated at a conference in Paris next year. While the United States and China announced a landmark agreement that includes new targets for carbon emissions, and Europe has pledged to reduce greenhouse gas emissions by 40 percent, India, the world’s third-largest emitter, has shown no appetite for such a pledge.

“India’s development imperatives cannot be sacrificed at the altar of potential climate changes many years in the future,” India’s power minister, Piyush Goyal, said at a recent conference in New Delhi in response to a question. “The West will have to recognize we have the needs of the poor.”

Mr. Goyal has promised to double India’s use of domestic coal from 565 million tons last year to more than a billion tons by 2019, and he is trying to sell coal-mining licenses as swiftly as possible after years of delay. The government has signaled that it may denationalize commercial coal mining to accelerate extraction.
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Study: Polar Bears Disappearing From Key Region

A key polar bear population fell nearly by half in the past decade, a new U.S.-Canada study found, with scientists seeing a dramatic increase in young cubs starving and dying.