Wednesday, October 29, 2014

Food 2.0: Chefs as Chemists




more cool pictures:
 http://www.nytimes.com/slideshow/2007/11/05/science/20071106_FOOD_SLIDESHOW_index.html


Tony Cenicola/The New York Times
Slices of eel are served with puffed yuzu, inspired by airy puffed snacks like Cheez Doodles, left. Framed by a reverse comma of tomato lettuce and powdered onions, beef tongue is accompanied by small pieces of lettuce and a high-tech version of fried mayonnaise.
In September, talking to an audience of chefs from around the world, Wylie Dufresne of WD-50 on the Lower East Side of Manhattan waxed enthusiastic about a type of ingredient he has been adding to his restaurant’s dishes.

Not organic Wagyu beef or newfound exotic spices or eye of newt and toe of frog, but hydrocolloid gums — obscure starches and proteins usually relegated to the lower reaches of ingredient labels on products like Twinkies. These substances are helping Mr. Dufresne make eye-opening (and critically acclaimed) creations like fried mayonnaise and a foie gras that can be tied into a knot.
Chefs are using science not only to better understand their cooking, but also to create new ways of cooking. Elsewhere, chefs have played with lasers and liquid nitrogen. Restaurant kitchens are sometimes outfitted with equipment adapted from scientific laboratories. And then there are hydrocolloids that come in white bottles like chemicals.
Xanthan gum, for instance, a slime fermented by the bacteria Xanthomonas campestris and then dried, is used in bottled salad dressing to slow the settling of the spice particles and keep water and oil from separating. Xanthan and other hydrocolloids are now part of the tool kit of high-end chefs.
“These ingredients are finding more and more of a footing in the traditional, free-standing restaurant,” said Mr. Dufresne (pronounced doo-FRAYN) at the Starchefs International Chefs Congress in New York.
He noted that the hydrocolloids he uses came from natural sources and often had a long history in the cooking of other cultures.
“In our ongoing search of working with hydrocolloids, we’re always trying to find interesting and new things and new applications,” said Mr. Dufresne, who at times sounded as if he were talking to chemists rather than chefs.
And rightly so. Cooking is chemistry, after all, and in recent decades scientists have given much closer scrutiny to the transformations that occur when foodstuffs are heated. That has debunked some longstanding myths. Searing meat does not seal in juices, for example, but high heat does induce chemical reactions among the proteins that make it tastier. The experimentation with hydrocolloids represents a rare crossover between the culinary arts and food science, two fields that at first glance would seem to be closely related but which have been almost separate. Food science arose in the 20th century as food companies looked for ways to make their products survive the trek to the supermarket and remain palatable. The long list of ingredients on a frozen dinner represents the work of food scientists in ensuring shelf life and approximating the taste of fresh-cooked food.
“Ten years ago, or maybe a little more than that, no chef in a serious restaurant would be caught dead using these ingredients,” said Harold McGee, author of “On Food and Cooking” (Scribner, 2004) and the “Curious Cook” column, which appears in the Dining section of The New York Times. “Because they were industrial stabilizers for the most part.”
Then a few chefs like Ferran AdriĆ  in Spain and Heston Blumenthal in England started experimenting. “They asked what can you do with these ingredients that you can’t do with other ingredients,” Mr. McGee said.
Despite its imposing name, a hydrocolloid is a simple thing. A colloid is a suspension of particles within some substance. A hydrocolloid is a suspension of particles in water where the particles are molecules that bind to water and to one another. The particles slow the flow of the liquid or stop it entirely, solidifying into a gel.
Cornstarch used as a thickener is a hydrocolloid. So is plain flour. But the properties of hydrocolloids differ widely, depending on their molecular structure and affinity for water.
Today, Grant Achatz, chef of Alinea in Chicago, uses agar-agar, which is a hydrocolloid made from seaweed that is best known for growing bacteria in petri dishes, and gelatin, a more familiar hydrocolloid made from collagen in meat, to make transparent sheets that he drapes over hot foods. For a dish made of a confit of beef short ribs, he wanted to add a taste of beer so he draped a veil flavored with Guinness on top — “a thin, flavorful glaze that ensured the diner would get some beer flavor in every bit of the dish,” Mr. Achatz said. Plain gelatin would simply melt, and ruin the effect.
Even chefs far from the avant-garde use hydrocolloids. David Kinch, the chef of Manresa Restaurant in Los Gatos, Calif., known for ultra-fresh and ultra-local ingredients, makes purees of vegetables. To keep water from leaking out, he adds a touch of xanthan gum.
One of the dishes Mr. Dufresne presented in his Starchefs talk was what he called “knot foie,” a result of experimentation combining xanthan gum with konjac flour, made from a tuber long used in Japanese cooking.
“We’ve had konjac flour in the kitchen for a long time, and we just hadn’t used it,” Mr. Dufresne said. “We realized, after reading, that it has a really interesting synergy with xanthan gum. It makes a kind of funky, strange gel on its own, but in conjunction with xanthan gum, which on its own won’t make a gel but is just a thickener, it makes a really interesting, very elastic product.”
He continued: “So we thought, well what could we take that normally wouldn’t behave like that but would be really interesting. And almost instantly, we came up with the idea of foie gras.”
One wall of the WD-50 kitchen, with metal shelves filled with white bottles of hydrocolloids, looks almost like a pharmacy. Mr. Dufresne’s reading material includes “Water-Soluble Polymer Applications in Foods” and “Hydrocolloid Applications: Gum Technology in the Food and Other Industries.”
Like scientists, Mr. Dufresne and his staff experiment, recording their observations and findings in notebooks. Using butter — much cheaper than foie gras — they began a series of trials in May to determine the ideal proportion of konjac to xanthan, which turned out to be 70 percent konjac, 30 percent xanthan in a 0.65 percent concentration.
“It’s a recipe,” Mr. Dufresne said.
In addition to flexible butter, Mr. Dufresne also has a recipe for a butter that does not melt in an oven. (That innovation has yet to find a place on his menu.) The latest experiments are how to make deep-fried hollandaise sauce, which he hopes to wrap into a variation of eggs benedict.
To make a flexible foie, a foie gras terrine is melted into liquefied fat, the xanthan and konjac are mixed in, and then a small amount of water and an egg yolk, which helps keep everything evenly suspended in the liquid, are blended in. The mixture is spread on a sheet, chilled, cut into strands and tied into knots. Hence, knot foie.
In the question-and-answer session, one person asked why Mr. Dufresne went to the trouble of making a foie gras terrine, a process that takes half a day of chilling, when the next step was melting it into a liquid.
“We were trying to be true and honest to that aspect of French cooking,” Mr. Dufresne replied. He paused before adding, “And do something kind of crazy with it.”

Tuesday, October 28, 2014

Methane-Munching Microbes Hit Rock Bottom

Certain methane-munching microbes have hit rock bottom, literally, living in rocks on the bottom of the ocean floor and soaking up large amounts of the potent greenhouse gas, according to new research. [Pictured: Active methane seep located 1,000 meters deep off the coast of Costa Rica.] (Photo : Victoria Orphan)
Certain methane-munching microbes have hit rock bottom, literally, living in rocks on the bottom of the ocean floor and soaking up large amounts of the potent greenhouse gas, according to new research.
These bottom-dwellers, described in the journal Nature Communications, are previously unknown methane sinks located in the deep sea, having such an effect that they impact global levels of the gas.
"We've recognized for awhile that the deep ocean is a sink for methane, but primarily it has been thought that it was only in the sediment," study researcher Jeffrey Marlow, a graduate student at Caltech, told Live Science. "The fact that it appears to be active in the rocks itself sort of redistributes where that methane is going."
According to the researchers, these microbes don't need oxygen to survive, but rather rely on sulfate ions present in the seawater for their energy needs. Their methane breathing system, the details of which still remain unclear, involves single-celled microorganisms dubbed "ANME" for "ANaerobic MEthanotrophs." ANME work closely with bacteria to consume methane using the ocean's sulfate.
"Without this biological process, much of that methane would enter the water column, and the escape rates into the atmosphere would probably be quite a bit higher," Marlow said in a statement.
The microbes, living in enormous rocks hundreds of feet tall, eat about 80 to 90 percent of the world's methane released through previously studied seeps, or cracks in the ocean floor.
Lead study author Victoria Orphan of Caltech and her colleagues found direct evidence of methane-breathing microbes in carbonate rocks collected from Hydrate Ridge, off the Oregon coast, as well as from cold seeps in Costa Rica and off the coast of northwestern California.
According to DNA analysis of rock samples, even though the microbes consumed methane at a slower rate than their sediment-dwelling cousins, there are presumably so many more microbes in the rock than in the dirt, its impact on global methane levels may be more significant.
Like notorious carbon dioxide, methane is a greenhouse gas capable of trapping heat from the Sun in the Earth's atmosphere. Though carbon dioxide (CO2) is more abundant, methane is actually 80 percent more potent at trapping heat than CO2.
And these methane-eating microbes, though out of site in the deep ocean, may be vital to reducing methane's role in global warming.
article
found by Danielle

Can chocolate boost memory?

Here's one for chocoholics to chew on. After consuming drinks enriched with compounds found in cocoa beans for three months, the performance of people aged 50 to 69 on a memory test was akin to someone several decades younger. Problem is, if you want such a benefit from eating chocolate, you would have to eat staggering amounts.
The small study is the latest to suggest that chemicals in cocoa called flavanols can have beneficial effects on the brain. Flavanols are a type of chemical found naturally in cocoa beans, blueberries, green tea and red wine. Previous studies have suggested that mice on a flavanol-rich diet showed enhanced memory and greater blood flow to certain areas of the brainScott Small, a neurologist at Columbia University in New York City, wanted to see what affect a similar regime might have on the human brain.
To find out, his team instructed 19 volunteers aged 50 to 69 to drink 900 milligrams a day of powdered cocoa flavanols mixed with water or milk. This dosage was spread over two drinks each day. Another 18 people had to drink a similar beverage that contained just 10 milligrams of the compounds.
Before and after the three months, people in both groups underwent fMRI scans. Comparing the scans revealed that after the regime, the high-dose flavanol drinkers had about 20 per cent more blood flowing to a particular section of their hippocampi, called the dentate gyrus, than they did before. The high-dose drinkers also had about this much more blood flow to the dentate gyrus than the low-flavanol group. Intriguingly, this region has been linked to age-related memory decline in people.

Enlist our microbiomes in the fight against cancer

There are subtle links between cancer cells (tinted green) and gut microbes (orange) (Image: Steve Gschmeissner/SPL)
Changes in our gut flora may encourage or battle cancer, so we need to get a few trillion of our foot soldiers on side, says a professor of medicine
THE human body is occupied by trillions of microorganisms, acquired at birth and maintained throughout our lifetime. Though we are mostly oblivious to thismicrobiome, it forms an intimate and essential part of our being. It is involved in many vital biological processes such as nutrition, the immune system and even mental health. Now evidence is mounting that the microbiome plays a role in cancer too.
In the past five years a comprehensive catalogue of the microorganisms living on and in the different surfaces and cavities of our bodies has been created – a sort of "getting to know your neighbours". This has revealed that the microbiome is a diverse community of more than 1500 species, with the vast majority residing in the intestine. We are just beginning to discover how these microbes influence the development and treatment of cancer.
The first evidence that "friendly" gut bacteria might have a darker side comes from studies in rodents, which developed fewer tumours when their microbiome had been wiped out, indicating the tumour-promoting potential of gut microbes.
In humans, the strongest evidence of the potential role of the microbiome in cancer comes from studies on colorectal cancer (CRC) – the third commonest form of cancer in the US and that country's second leading cause of cancer deaths. Recent research on people with CRC showed that their intestinal microbial communities become unbalanced. For example, compared with healthy people, the stools of people with CRC contain less of the bacterial groups Lachnospiraceae and Roseburia but an increased abundance of others such as Enterococcus and Streptococcus.
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How might a "dysbiotic" microbiome play a role in cancer? Roseburiamicrobes, for instance, produce high quantities of butyrate, so fewer of these organisms in the intestines could result in smaller amounts of protective butyrate. Studies in mice showed that low levels of colonic butyrate could foster the development of CRC.
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How else could gut microbes play a role in cancer? Recent evidence indicates that bacteria may produce noxious agents – gases, toxins, radical oxygen species – that can cause instabilities in the host's genetic material. For instance, the bacterium E. coli is found in abundance in the intestinal mucosa of people with CRC, compared with people without CRC. Interestingly, genomic analysis of these CRC-associated E. coli revealed the presence of a cluster of genes responsible for producing a substance called colibactin. This natural product triggers DNA breakage and genomic instability in different cells, including cells lining the intestine.

Friday, October 24, 2014

European Leaders Agree on Targets to Fight Climate Change

The 28 leaders of the European Unionagreed early on Friday on targets for protecting the climate and generating greener power despite deep divisions among their nations over how to produce energy.
The main target that won approval was a pledge to slash emissions by at least 40 percent, compared with 1990 levels, by 2030.
The new target “will ensure that Europe will be an important player, will be an important party, in future binding commitments of an international climate agreement,” Angela Merkel, the German chancellor, said at an early-morning news conference.
The accord makes the European Union the first major global emitter to put its position on the table ahead of an important United Nations climate meeting in Paris at the end of 2015.
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The pledge to cut emissions by 40 percent would eventually come with legally binding targets for each of the bloc’s member countries to share the burden equitably.
The bloc also agreed on a target of generating at least 27 percent of its energy from renewable sources, a goal that will be binding at the European Union level but not the national level. A separate target for improving energy efficiency by at least 27 percent was “indicative” only, meaning it would not be binding even at the bloc level. Both of those targets raised questions about their enforceability.
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Ebola Updates




30 OCTOBER 2014 | RESEARCH REPORT

Strategies for containing Ebola in West Africa

A combination of hygienic practices could feasibly check Ebola within six months.
30 OCTOBER 2014 | RESEARCH REPORT

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

Intercrossed mice infected with Ebola virus show the spectrum of pathology from prolonged coagulation to total resistance.

What does Ebola actually do?

Is the Ebola Epidemic Ending in Africa?





Photo
Health workers at an Ebola treatment unit in Liberia.Credit Daniel Berehulak for The New York Times

A: 
No one knows exactly what is going on in West Africa. Several medical groups, like Doctors Without Borders, are reporting that they suddenly have far more beds than patients. In some cases, there are empty beds at centers where, just a few weeks ago, people were dying on the streets outside because there was no room.
The trend is especially noted in Liberia, the hardest-hit country. Laboratories are getting fewer samples to test. Ambulance crews are picking up fewer bodies. The World Health Organization confirmed that new cases were dropping.
But health authorities are warning that it is too early to celebrate.
It is important to remember that this happened once before, on a smaller scale. In March, after alarming reports from Guinea that a rural outbreak had reached the capital, the W.H.O. and the Centers for Disease Control and Prevention sent experts in to help. The epidemic spread to Sierra Leone, and then to Liberia. But cases grew only slowly, and by May, most of the experts were withdrawn. At the time, there was more worry about MERS in Saudi Arabia.
In early August, the chief scientist for Britain’s foreign aid agency said the “end of the epidemic was in sight.” He was wrong. About 800 people were known to be dead then. Cases had actually begun to explode in July, and now about 5,000 are dead.
There are some theories as to why the numbers seem to be going down. The leading one is that more West Africans now believe that Ebola exists, are afraid of it, and are touching each other less.
In that way, it is like lung cancer, only on a speeded-up time scale. It took 30 years for Americans to fully accept that smoking caused lung cancer. Once they believed, fewer started smoking. Deaths from lung cancer are now much lower than they used to be because many Americans in their 50’s and 60’s didn’t start as teenagers, or quit. But you wouldn’t say that the lung cancer epidemic is over.
Because poor West Africans often have many people sleeping in one room, Ebola spreads in households. Because the incubation period is up to 21 days, it often kills the family slowly, one by one. But for each other family that keeps the virus from entering its household, that can mean five or six fewer deaths.
Other theories are that tens of thousands of home-care kits have been handed out. They contain gloves, bleach, a bucket, plastic bags and a bleach sprayer. Using them around the sick, and especially during burials, may have helped.
Alternatively, hospitals may be empty because more people are dying at home. In Liberia, it has been reported that families are refusing to bring in their relatives because, if they die, they will be cremated.
Another report is that taxi and minibus drivers are refusing to take passengers who are bleeding or vomiting to hospitals. That forces them to die at home – which is cruel, but could slow the spread of disease to other passengers.
It is also important to remember that epidemics typically come in waves. The reasons for some are obvious, like the weather: flu cases rise in winter, polio cases rise in summer. Pox diseases like smallpox, measles and chickenpox used to surge every few years after a new set of young children was born. For other diseases, the reasons are not clear. Ebola may simply be having a moment between waves.










Photo

A nurse who had worked with Ebola patients in West Africa was placed under quarantine at University Hospital shortly after she landed at Newark Liberty International Airport on Friday.CreditRobert Stolarik for The New York Times

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A nurse who was being quarantined at a New Jersey hospital after working with Ebola patients in Sierra Leone criticized her treatment on Saturday as an overreaction after an initial test found that she did not have the virus.
“I am scared about how health care workers will be treated at airports when they declare that they have been fighting Ebola in West Africa,” the nurse, Kaci Hickox, wrote in an essay on the website of The Dallas Morning News, in collaboration with a friend who works for the paper. “I am scared that, like me, they will arrive and see a frenzy of disorganization, fear, and most frightening, quarantine.”
She described being held in isolation for about seven hours at Newark Liberty International Airport on Friday, left alone for long stretches and given only a granola bar when she said she was hungry.
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Ebola Vaccine, Ready for Test, Sat on the Shelf
Almost a decade ago, scientists from Canada and the United States reported that they had created a vaccine that was 100 percent effective in protecting monkeys against the Ebola virus. The results werepublished in a respected journal, and health officials called them exciting. The researchers said tests in people might start within two years, and a product could potentially be ready for licensing by 2010 or 2011.
It never happened. The vaccine sat on a shelf. Only now is it undergoing the most basic safety tests in humans
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Nina Pham, Dallas Nurse Who Had Ebola, to Be Released From Hospital

Ebola Vaccine Trials Planned for December

Participants in Liberia and Sierra Leone would receive experimental vaccines that could lead to mass inoculations by spring, health officials said Friday.

Tuesday, October 21, 2014

Hoverboard? Still in the Future

NYTimes

Testing out the Hendo Hoverboard, which was developed by a couple in Los Gatos, Calif.
Jason Henry for The New York Times
Testing out the Hendo Hoverboard, which was developed by a couple in Los Gatos, Calif.
For the last 25 years, inventors like garage tinkerers, physics professors and engineers have been trying to make a hovering skateboard.